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Spinal Cord Injury Repair Research
Latest pioneering research projects supported by the Roman Reed Spinal Cord Injury Research Act of California.

Presented at the 8TH Roman Reed Research Meeting / Neural Regeneration Consortium

hans keirstead
Use of a Viral Vector Approach to Delete PTEN in the Motor Cortex and Promote Axon Regeneration after Spinal Cord Injury
Oswald Steward, Ph.D., UC Irvine
Director of the Roman Reed Spinal Cord Injury Research Fund and Core Laboratory
Director & Professor, Reeve-Irvine Research Center; Professor, Departments of Anatomy and Neurobiology, Neurobiology and Behavior and Neurosurgery

hans keirstead
Novel Quantitative and Functional Outcome Measures for Thoracic Spinal Cord Function after Traumatic Spinal Cord Injury
Suzy Kim, M.D., UC Irvine
Medical Director, Spinal Cord Injury Program; Assistant Clinical Professor Departments of Orthopaedic Surgery & Physical Medicine & Rehabilitation; Scientific Liaison, Reeve-Irvine Research Center
Development of an Electronic Bridge over the Lesion between Fore and Hind-limbs to Facilitate Quadrupedal Stepping after a Complete Spinal Cord Transection
V. Reggie Edgerton, Ph.D., UCLA
Professor, Departments of Neurobiology, Physiological Science and the Brain Research Institute

WNT Signaling in Central Nervous System Regeneration
Yimin Zou, Ph.D., UCSD
Associate Professor, Division of Biological Sciences, Section of Neurobiology
Edmund Hollis II, Ph.D.,
Zou Lab post-doctoral fellow
hans keirstead
The Effect of HBOT on Acute Spinal Cord Injury & Disorders Rehabilitation Outcome
Sophia Chun, M.D., VA Long Beach;
UC Irvine

Chief, Spinal Cord Injury Center, Veterans Affairs, Long Beach Healthcare System, CA; Asst. Clinical Professor, Department of Physical Medicine and Rehabilitation, UCI

hans keirstead
hans keirstead
UC Primate Consortium: Axonal Plasticity and Regeneration
Mark Tuszynski, M.D.,

Director & Professor, Center for Neural Repair, Department of Neurosciences (Pictured left)
Ephron Rosenzweig, Ph.D.
Asst. Project Scientist, Center for Neural Repair, Department of Neurosciences (Pictured right)
hans keirstead
Brain Computer Interface (BCI) Controlled Walking Simulator
Zoran Nenadic, D.Sc., UC Irvine
Assistant Professor, Department of Electrical Engineering and Computer Science (Pictured)
Luis Chui, M.D., UC Irvine, VA Long Beach
Health Sciences Clinical Professor of Neurology, UC Irvine MDA/ALS and Neuromuscular Center; Attending Physician, director of Outpatient Neurology and neuromuscular clinics. Long Beach Veterans Affairs Medical Center.
An Do, M.D., UC Irvine
Resident Physician in Neurology, UC Irvine Medical Center

hans keirstead
Engineering the Corticospinal Tract as a High-Throughput Model to Study Spinal Cord Injury
Lawrence Recht, M.D., Stanford University
Professor of Neurology, Stanford University School of Medicine (Pictured)
James Weimann, Ph.D., Stanford University
Senior Research Scientist, Department of Neurology
hans keirstead
An Inducible Receptor Tyrosine Kinase for Axonal Regeneration
Armin Blesch, Ph.D., UCSD
Associate Professor, Department of Neurosciences, Center for Neural Repair

Links to Supported Research:
Oligodendrocyte Progenitors Show Functional Improvements in Spinal Cord Injuries
Geron Corporation (Nasdaq:GERN) announced today the publication of studies showing that oligodendrocyte progenitors, differentiated from human embryonic stem cells (hESCs), produce functional improvements in rats with spinal cord injuries.
These studies in Dr. Keirstead's laboratory were conducted with support from Geron Corporation, a University of California Discovery Grant and the Roman Reed Spinal Cord Injury Fund of California.

UCLA scientists restore walking after spinal cord injury
Study shows nervous system can reorganize itself, use new pathways to issue commands to move.
The UCLA study was supported by grants from the National Institute of Neurological Disease and Stroke, the Adelson Medical Foundation, the Roman Reed Spinal Cord Injury Research Fund of California and the Christopher and Dana Reeve Foundation.

UCSF Study Finds Nerve Regeneration Is Possible In Spinal Cord Injuries
A team of scientists at UCSF has made a critical discovery that may help in the development of techniques to promote functional recovery after a spinal cord injury.
Study co-authors include first-author Simona Neumann, PhD, and Kate Skinner, MD, both of UCSF. The research was funded by the Roman Reed Spinal Cord Injury Research Fund of California and the National Institutes of Health.

Blocking immune response to spinal cord injury can improve recovery
People who suffer spinal cord injuries may have a greater chance of recovery if treated with drugs that block the body's own immune response to the initial trauma, researchers from the Reeve-Irvine Research Center at UC Irvine have found.
The study was supported by the Roman Reed Spinal Cord Injury Research Fund of California, Research for the Cures and individual donations to the Reeve-Irvine Research Center.

Update on Spinal Cord Injury Regeneration Research Mark Tuszynski, M.D., Ph.D. Director, Center for Neural Repair University of California, San Diego
This article will review recent research in the field of spinal cord injury regeneration, and will try to provide a realistic assessment of how and when some of this research may find its way to human clinical trials.
The California legislature passed the Roman-Reed Bill in the year 2000. The Roman-Reed bill provided funding of $1 million per year for spinal cord research in California .

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